Early Pregnancy Sex Steroids and Maternal Breast Cancer: A Nested Case–Control Study
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چکیده
منابع مشابه
Early pregnancy sex steroids and maternal risk of epithelial ovarian cancer.
Well-established associations between reproductive characteristics and epithelial ovarian cancer (EOC) support an involvement of sex steroid hormones in the etiology of EOC. Limited previous studies have evaluated circulating androgens and the risk of EOC, and estrogens and progesterone have been investigated in only one of the previous studies. Furthermore, there is little data on potential he...
متن کاملSex Steroids and Breast Cancer: An Overview
Sex steroids, also known as sex hormones are synthesized naturally by the gonads (ovaries or testes). The two main classes of sex steroids, androgens and estrogens, are crucial hormones for the proper development and function of the body; they regulate sexual differentiation, the secondary sex characteristics, and sexual habits. They are also well known to influence many common cancers, especia...
متن کاملPostmenopausal serum sex steroids and risk of hormone receptor-positive and -negative breast cancer: a nested case-control study.
Prediagnostic endogenous sex steroid hormone levels have well established associations with overall risk of breast cancer. While evidence toward the existence of distinct subtypes of breast cancer accumulates, few studies have investigated the associations of sex steroid hormone levels with risk of hormone receptor [estrogen receptor (ER) and/or progesterone receptor (PR)] defined breast cancer...
متن کاملCirculating sex steroids during pregnancy and maternal risk of non-epithelial ovarian cancer.
BACKGROUND Sex steroid hormones have been proposed to play a role in the development of non-epithelial ovarian cancers (NEOC) but so far no direct epidemiologic data are available. METHODS A case-control study was nested within the Finnish Maternity Cohort, the world's largest biorepository of serum specimens from pregnant women. Study subjects were selected among women who donated a blood sa...
متن کاملSex steroids and cervical cancer.
During the 19th century, studies indicated that reproductive events were involved in cervical cancer. Human papillomavirus (HPV) infection is a prerequisite for development of cancer, but co-factors, among them the action of sexual steroid hormones, are necessary. Childbirth has been an important risk factor but now probably plays a minor role in the industrialized world, where parity is low. L...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2014
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-14-2150